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Which study design compares a diseased group with a non-diseased group?

  1. Cross-sectional Study

  2. Prospective Cohort Study

  3. Case Control Study

  4. Randomized Control Trial

The correct answer is: Case Control Study

A case-control study is a research design that specifically looks at two groups: individuals who have a particular disease or condition (the case group) and individuals who do not have the disease (the control group). This study design is particularly useful for identifying factors that may be associated with a disease, as it allows researchers to retrospectively determine exposures or characteristics that may differ between the two groups. In a case-control study, researchers start with the outcome (the disease) and look backward to assess potential risk factors or exposures that could have contributed to the disease. This method is advantageous for studying rare diseases, as it focuses on individuals who already have the condition, making it easier to recruit participants. By comparing the two groups, the study aims to elicit patterns or associations that help in understanding the etiology of the disease. In contrast, a cross-sectional study provides a snapshot of both diseased and non-diseased individuals at a single point in time without considering exposure history. A prospective cohort study follows a group of individuals over time to see who develops the disease, starting with non-diseased individuals. A randomized control trial involves randomly assigning participants to groups for intervention purposes rather than dealing with existing disease status. Thus, the hallmark of a case-control