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Which of the following is NOT a function of the liver?

  1. Clotting factor formation

  2. Prothrombin formation

  3. Decrease blood pressure

  4. Glucose metabolism

The correct answer is: Decrease blood pressure

The liver plays a crucial role in numerous physiological processes essential for maintaining overall health. One of its primary functions includes the formation of clotting factors, which are vital for the blood coagulation process. Specifically, it synthesizes several proteins and factors that are integral to clotting, making options related to clotting factor and prothrombin formation accurate representations of liver functions. In addition, the liver is a key player in glucose metabolism, responsible for the regulation of blood sugar levels through processes such as gluconeogenesis and glycogenolysis. This means it can both store and release glucose as needed to maintain energy balance. However, the statement about decreasing blood pressure does not correctly represent a direct function of the liver. While liver health can influence vascular resistance and blood flow, the primary mechanisms for regulating blood pressure lie more in the cardiovascular system and the actions of hormones rather than being a direct function of the liver itself. Thus, identifying the function that does not pertain to the liver leads to the correct conclusion that decreasing blood pressure is not one of its roles.