The Role of Gastrin: A Key Hormone in Your Stomach

What hormone is released from G Cells in the stomach?

• A. Secretin
• B. Cholecystokinin
• C. Gastrin
• D. Gastric inhibitory peptide

Answer: (C)

The hormone released from G cells in the stomach is gastrin, which is a key player in the digestive process. G cells, located primarily in the gastric mucosa, respond to various stimuli, such as the presence of food in the stomach, by secreting gastrin into the bloodstream. Gastrin has several vital functions: it stimulates the secretion of gastric acid (hydrochloric acid) from the parietal cells in the stomach, which is critical for the digestion of food. It also promotes gastric motility, enhancing the movement of the stomach muscles to facilitate digestion and mixing of food with gastric juices. Additionally, gastrin aids in maintaining the integrity of the gastric mucosa through its trophic effects. The other hormones listed have different sources and functions. Secretin is produced by the S cells in the duodenum and plays a role in regulating water homeostasis and acidity by stimulating the pancreas to release bicarbonate. Cholecystokinin, mostly produced in the cells of the small intestine, is involved in stimulating the gallbladder to release bile and promoting the release of digestive enzymes from the pancreas. Gastric inhibitory peptide (GIP) is also produced in the small intestine and helps to inhibit gastric motility and secretion

Let’s talk about gastrin – an unsung hero in the realm of digestive hormones. Ever heard of G cells? These special cells, nestled in the stomach lining, are responsible for producing gastrin. You probably didn’t realize just how pivotal gastrin is for your digestive health. So, let’s unpack this vital hormone, shall we?

First off, what exactly is gastrin? In simple terms, it’s a hormone released from G cells when food makes its grand entrance into your stomach. You can think of gastrin as your body’s way of saying, “Hey, it’s time to digest!" When food hits the stomach, G cells spring into action, releasing gastrin into the bloodstream. But what’s the big deal?

Gastrin's primary job is to stimulate the secretion of gastric acid, specifically hydrochloric acid (HCl). This acid is essential for breaking down the food you’ve just eaten. If you’ve ever experienced that gnawing sensation after a meal, it might be your body craving that potent gastric acid to aid digestion. Gastrin essentially revs up the engine of your digestive system.

But wait, gastrin doesn’t stop there! It also enhances gastric motility. Think of it as the signal for your stomach muscles to start churning and mixing food with those precious gastric juices. It's like a dance party in there, where the food gets all mixed up for better absorption. Without gastrin, dinner could get pretty dull – or worse, unnecessarily uncomfortable.

Now, while gastrin plays a leading role, it’s a team player too, working alongside other hormones in the digestive system. For example, let’s not forget about secretin – the hormone that swings into action to regulate acidity after food passes into the duodenum. Then there’s cholecystokinin, which nudges your gallbladder to release bile, aiding in fat digestion. And let’s throw in gastric inhibitory peptide (GIP), which works to slow down gastric motility when necessary. It’s all about balance, folks!

You might wonder why knowing about gastrin matters beyond just passing that Advanced Dental Admission Test (ADAT). Well, understanding these processes gives you insight into overall gastrointestinal health – and that’s pretty important, especially if you’re aiming for a career in dentistry or healthcare. Everything's connected, and comprehending how one hormone affects another can be the key to distinguishing yourself in the field.

Feeling overwhelmed? Don't sweat it. It’s normal. As a student preparing for the ADAT, you’ll likely face plenty of questions about hormones like gastrin, and trust me, grasping these concepts can make all the difference on test day. Think about it as building the foundation of your understanding in a world that's all about connections — connections between hormones, functions, and why they matter in a clinical context.

To wrap it all up, gastrin is not just a minor player; it's a crucial part of your digestive playbook. By stimulating acid production and promoting gastric motility, it ensures everything runs smoothly after that last bite. And if you keep gastrin in your back pocket during your studies, you just might find yourself better equipped to tackle questions on hormones when the time comes. Happy studying!