Advanced Dental Admission Test (ADAT)

What condition is associated with Klebsiella pneumoniae?

1. Aspiration pneumonia in chronic alcoholics and diabetics

2. Chronic infection of the skin

3. Type 2 diabetes complications

4. Bone infections in immunocompromised patients

The correct answer is: Aspiration pneumonia in chronic alcoholics and diabetics

Klebsiella pneumoniae is primarily known for causing respiratory infections, especially pneumonia, which is commonly seen in individuals with predisposing factors such as chronic alcoholism and diabetes. The organism can be introduced into the lungs through aspiration, where gastric contents, including bacteria, are inhaled, leading to infection. Chronic alcoholics often exhibit a weakened immune response and impaired ability to clear aspirated material, creating an environment conducive to infection. Likewise, patients with diabetes can have altered immune functions and may present with aspiration pneumonia due to poor management of their condition, making them more susceptible to infections caused by Klebsiella pneumoniae. In contrast, chronic infections of the skin are more typically linked to different pathogens, while type 2 diabetes complications generally involve metabolic issues rather than direct infections by Klebsiella. Although bone infections can occur in immunocompromised patients, they are not specifically associated with Klebsiella pneumoniae and are more often caused by other bacteria in such contexts. Therefore, the association of Klebsiella pneumoniae with aspiration pneumonia, particularly in populations like chronic alcoholics and diabetics, is the key point that highlights the correct option.