Advanced Dental Admission Test (ADAT)

Doxycycline is known to be effective in treating which condition?

1. Chronic gingivitis

2. Localized aggressive periodontitis associated with Actinobacillus actinomycetemcomitans

3. Oral candidiasis

4. Acute periapical abscess

The correct answer is: Localized aggressive periodontitis associated with Actinobacillus actinomycetemcomitans

Doxycycline is indeed recognized for its effectiveness in treating localized aggressive periodontitis, particularly when associated with the bacterium Actinobacillus actinomycetemcomitans. This antibiotic is a member of the tetracycline class and possesses unique properties that inhibit bacterial protein synthesis, which makes it particularly suitable for targeting specific pathogens involved in periodontal disease. In the case of localized aggressive periodontitis, doxycycline not only helps reduce the bacterial load but also has anti-inflammatory properties that aid in managing the condition. In contrast, chronic gingivitis generally requires more conservative treatment, such as improved oral hygiene practices, rather than antibiotic therapy. Oral candidiasis is primarily treated with antifungal medications rather than antibiotics like doxycycline. Similarly, an acute periapical abscess typically warrants endodontic treatment or drainage rather than antibiotic therapy alone, although antibiotics may sometimes be used as an adjunct. Thus, doxycycline's specific role in managing localized aggressive periodontitis stands out for its clinical efficacy against this dental condition.